Promethazine with codeine syrup is indicated for your short-term relief of coughs and upper respiratory symptoms associated with allergy or even the prevalent cold.
Anticholinergics – Concomitant use of other brokers with anticholinergic Houses should be carried out with warning.
Unresponsive Cough The dosage of Promethazine HCl and Codeine Phosphate Oral Option really should not be enhanced if cough fails to respond; an unresponsive cough should be reevaluated in 5 days or quicker for feasible underlying pathology, like foreign entire body or reduced respiratory tract illness [see Dosage and Administration (two.3)].
The narcotic antagonist, naloxone hydrochloride, could be administered when significant respiratory despair occurs with promethazine and codeine; any depressant outcomes of promethazine are usually not reversed with naloxone. Diazepam could possibly be applied to control convulsions. Stay clear of analeptics, which may induce convulsions. Acidosis and electrolyte losses needs to be corrected. An increase in temperature or pulmonary issues may possibly signal the need for institution of antibiotic therapy.
There is absolutely no general settlement about precise pharmacological therapy regimens for uncomplicated NMS.
Lactation At the very least 1 death was described inside a nursing infant who was subjected to higher amounts of morphine in breast milk as the mom was an ultra-speedy metabolizer of codeine.
Read the Medication Guidebook supplied by your pharmacist Before you begin getting promethazine/phenylephrine/codeine and every time you obtain a refill. When you've got any queries, ask your health practitioner or pharmacist.
Chances are you'll develop tolerance to this medication. Tolerance signifies that you will want the next dose with the medication for soreness aid. Tolerance is normal and is anticipated if you take this medication for years.
Examine the Medication Information provided by your pharmacist Before you begin using codeine/promethazine and each time you obtain a refill. When you've got any issues, question your medical professional or pharmacist.
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Take this drugs only as directed by Promethazine codeine syrup your medical doctor. Never get much more of it, don't choose it extra generally, and do not just take it for an extended time than your medical doctor purchased.
If you have soreness, you do have a professional medical rationale to acquire suffering medication. Your care staff will show you just how much medication to acquire. If your care group desires you to halt the medication, the dose are going to be slowly reduced after some time to stop any Unwanted effects.
Released scientific tests with codeine have noted inconsistent findings and have crucial methodological limits (see Information). You can find experiences of respiratory melancholy when codeine is utilised in the course of labor and shipping (see Clinical Considerations).
INDICATIONS AND Use Promethazine HCl and Codeine Phosphate Oral Solution is a mix of codeine, an opioid agonist; and promethazine, a phenothiazine, indicated for the non permanent relief of cough and higher respiratory signs and symptoms affiliated with allergy or perhaps the frequent cold in sufferers 18 a long time of age and more mature. (one)